Combinations of candidates: a TPP for malaria treatment
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چکیده
The challenge of combining these candidates to design an ideal medicine against malaria (Table 5) is formidable. There are still many unknown factors, not the least of which is that only a limited number of new classes of molecules have reached clinical evaluation. It is clear that a single molecule can have more than one attribute: a molecule can for example meet the criteria of more than one candidate profile (Figures 4 and 5), but it is essential that combinations of molecules will be needed, not least to combat resistance.
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